Tristearin (CAS: 555-43-1): Properties, Applications, and Safety

Tristearin, also known as glyceryl tristearate or glyceryl tristearoyl triester, is a triglyceride derived from stearic acid and glycerol. With the chemical formula C57H110O6, it is a solid, waxy compound widely used in industrial and cosmetic applications. The CAS registry number for Tristearin is 555-43-1.

Chemical and Physical Properties

– Chemical Name: Glyceryl tristearate
– CAS Number: 555-43-1
– Molecular Formula: C57H110O6
– Molecular Weight: 891.48 g/mol
– Appearance: White to off-white solid or powder
– Melting Point: Approximately 70–73°C
– Solubility: Insoluble in water; soluble in organic solvents such as ethanol and chloroform

Tristearin is a symmetrical triglyceride, where all three hydroxyl groups of glycerol are esterified with stearic acid (C18:0), a saturated long-chain fatty acid. Its high melting point and waxy nature make it suitable for applications requiring solid fat-like substances.

Industrial Applications

1. Cosmetic and Personal Care Products

Tristearin is used in the formulation of:
– Creams and lotions as an emollient and thickener
– Lipsticks and solid makeup as a structuring agent
– Soaps and bath products for enhanced texture and consistency

It provides a smooth application feel and helps stabilize emulsions.

2. Pharmaceutical and Nutraceutical Industries

Though not used as an active ingredient, Tristearin is utilized as:
– An excipient or lubricant in tablet manufacturing
– A release agent in capsule production
– A coating material for controlled-release drug delivery systems

3. Polymer and Plastics Manufacturing

Tristearin can act as a:
– Lubricant or slip agent in plastic processing
– Mold release agent for rubber and plastic products
– Additive in biodegradable plastics to enhance flow and processing

4. Lubricants and Greases

Due to its fatty acid ester structure, Tristearin can function as a:
– Base oil or thickener in specialty lubricants
– Binder in solid lubricating formulations

Sustainability and Biodegradability

Tristearin is a biodegradable and environmentally friendly compound derived from renewable resources such as animal fats or vegetable oils. Its use in eco-friendly materials, such as bioplastics and green lubricants, aligns with the growing demand for sustainable solutions in industrial sectors.

Safety and Handling

While Tristearin is considered non-toxic and non-irritating, standard handling practices should be followed:
– Use protective gloves and eyewear when handling in industrial settings
– Store in a cool, dry, well-ventilated area away from strong oxidizing agents
– Follow local regulations for disposal and spillage management

Material Safety Data Sheets (MSDS) should always be consulted for up-to-date safety information.

Conclusion

Tristearin (CAS: 555-43-1) is a versatile compound with valuable properties for industrial applications ranging from cosmetics and pharmaceuticals to plastics and lubricants. Its biodegradability, stability, and functional properties make it an attractive option for manufacturers seeking high-performance and environmentally conscious ingredients.

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